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Reported effects are generally mild injection-site reactions, fatigue, lightheadedness after a dose

Extrapolating mecasermin data to IGF-1 LR3 is problematic because the pharmacokinetics and tissue exposure profiles differ significantly due to the binding protein modifications

Administering hepsin mitigates drug-induced liver damage by acetaminophen in hepsin / mice

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Nat Commun 10:905 Laforest-Lapointe I, Becker AB, Mandhane PJ, Turvey SE, Moraes TJ, Sears MR, Subbarao P, Sycuro LK, Azad MB, Arrieta MC (2021) Maternal consumption of artificially sweetened beverages during pregnancy is associated with infant gut microbiota and metabolic modifications and increased infant body mass index